Search results for "Botulinum toxin injection"

showing 3 items of 3 documents

Botulinum Toxin Injection Plus Topical Diltiazem for Chronic Anal Fissure: A Randomized Double-Blind Clinical Trial and Long-term Outcome.

2021

BACKGROUND: Chemical sphincterotomy avoids the risk of permanent incontinence in the treatment of chronic anal fissure, but it does not reach the efficacy of surgery and recurrence is high. Drug combination has been proposed to overcome these drawbacks.; OBJECTIVE: This study aimed to compare the clinical, morphological, and functional effects of combined therapy with botulinum toxin injection and topical diltiazem in chronic anal fissure and to assess the long-term outcome after healing.; DESIGN: This is a randomized, controlled, double-blind, 2-arm, parallel-group trial with a long-term follow-up.; SETTINGS: This study was conducted at a tertiary care center.; PATIENTS: A total of 70 cons…

Gynecologymedicine.medical_specialtybusiness.industryGastroenterologyChronic anal fissureBotulinum toxin injectionGeneral MedicineTopical diltiazemPlaceboSymptomatic reliefClinical trialDouble blindFissure recurrenceBotulinum toxinmedicineCombined therapyDiltiazembusinessChronic anal fissuremedicine.drug
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What could have caused this weight loss?

2016

International audience; Achalasia is rare and often diagnosed late.It is characterized by functional gastro-oesophageal sphincter obstruction.Aspiration pneumonia may complicate the achalasia.Intrasphincteric botulinum toxin injection is one of the main treatments for achalasia.

medicine.medical_specialtyBotulinum ToxinsAchalasiaBotulinum toxin injection[ SDV.MHEP.GEG ] Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontologyAspiration pneumoniaPneumonia AspirationGastroenterologydigestive systemEndoscopy Gastrointestinal03 medical and health sciences0302 clinical medicineWeight lossInternal medicineWeight LossInternal Medicinemedicineotorhinolaryngologic diseasesHumans030212 general & internal medicineComputingMilieux_MISCELLANEOUSAged 80 and overmedicine.diagnostic_test[SDV.MHEP.GEG] Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontologybusiness.industry[SDV.MHEP.GEG]Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontologydigestive oral and skin physiologyAchalasia[SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterologymedicine.disease[SDV.MHEP.HEG] Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterologydigestive system diseases3. Good healthEndoscopyEsophageal AchalasiaPneumoniamedicine.anatomical_structureSphincter030211 gastroenterology & hepatologyFemale[ SDV.MHEP.HEG ] Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologiemedicine.symptombusiness
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Fisurectomy and anoplasty with botulinum toxin injection in patients with chronic anal posterior fissure with hypertonia: a long-term evaluation.

2020

AbstractChronic anal fissure’s (CAF) etiopathogenesis remain unclear. CAF of the posterior commissure (CAPF) are often characterized by internal anal sphincter (IAS) hypertonia. The treatment of this disease aimed to reduce IAS hypertonia. Due to the high rate of anal incontinence after LIS, the employment of sphincter preserving surgical techniques associated to pharmacological sphincterotomy appears more sensible. The aim of our study is to evaluate the long-term results of fissurectomy and anoplasty with V–Y cutaneous flap advancement associated to 30 UI of botulinum toxin injection for CAPF with IAS hypertonia. We enrolled 45 patients undergone to fissurectomy and anoplasty with V–Y cut…

medicine.medical_specialtyBotulinum ToxinsUltrasound waveAnal CanalBotulinum toxin injectionInternal anal sphincterFissurectomyBotulinum toxinSphincterotomyMuscle HypertoniamedicineHumansIn patientProspective StudiesAnal fissurebusiness.industryAnoplastymedicine.diseaseBotulinum toxinSurgerymedicine.anatomical_structureTreatment OutcomeAnal fissure Anoplasty Botulinum toxin Fissurectomy Proctology SphincterotomyChronic DiseaseSphincterHypertoniaSurgeryOriginal ArticleFissure in Anomedicine.symptomProctologyAnal fissurebusinessmedicine.drugUpdates in surgery
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